David C Warltier Selected Research

sepiapterin

1/2016	Chronic Co-Administration of Sepiapterin and L-Citrulline Ameliorates Diabetic Cardiomyopathy and Myocardial Ischemia/Reperfusion Injury in Obese Type 2 Diabetic Mice.
1/2013	Impairment of endothelial-myocardial interaction increases the susceptibility of cardiomyocytes to ischemia/reperfusion injury.
11/2011	Decreased tetrahydrobiopterin and disrupted association of Hsp90 with eNOS by hyperglycemia impair myocardial ischemic preconditioning.
3/2010	Hyperglycemia adversely modulates endothelial nitric oxide synthase during anesthetic preconditioning through tetrahydrobiopterin- and heat shock protein 90-mediated mechanisms.

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David C Warltier Research Topics

Disease

40	Infarction (Infarctions) 01/2017 - 01/2002
37	Myocardial Infarction 01/2017 - 01/2002
21	Ischemia 01/2018 - 05/2002
16	Reperfusion Injury 01/2018 - 03/2004
16	Coronary Occlusion 02/2009 - 03/2002
11	Hyperglycemia 07/2013 - 01/2002
8	Myocardial Ischemia (Ischemic Heart Diseases) 01/2018 - 11/2002
8	Hypoxia (Hypoxemia) 09/2013 - 11/2005
7	Hyperplasia 06/2006 - 07/2004
3	Diabetes Mellitus 01/2016 - 06/2002
3	Delirium 08/2010 - 10/2009
2	Left Ventricular Dysfunction 01/2018 - 12/2003
2	Diabetic Cardiomyopathies 01/2016 - 01/2016
2	Emergence Delirium 12/2009 - 10/2009
2	Alcoholism (Alcohol Abuse) 11/2009 - 03/2007
1	Myocardial Stunning (Stunned Myocardium) 01/2018
1	Body Weight (Weight, Body) 01/2018
1	Fibrosis (Cirrhosis) 01/2017
1	Heart Diseases (Heart Disease) 01/2016
1	Type 2 Diabetes Mellitus (MODY) 04/2014
1	Post-Traumatic Stress Disorders (Post Traumatic Stress Disorder) 12/2010
1	Cognitive Dysfunction 12/2010
1	Postoperative Cognitive Complications 12/2009

Drug/Important Bio-Agent (IBA)

37	Isoflurane FDA LinkGeneric 01/2018 - 01/2002
27	triphenyltetrazoliumIBA 10/2009 - 01/2002
21	Anesthetics (Anesthetic Agents)IBA 01/2018 - 01/2002
8	Nitric Oxide (Nitrogen Monoxide)FDA Link 01/2016 - 08/2006
8	Adenosine Triphosphate (ATP)IBA 08/2008 - 01/2002
8	Saline SolutionIBA 09/2007 - 05/2003
7	Nitric Oxide Synthase Type III (Endothelial Nitric Oxide Synthase)IBA 01/2018 - 02/2006
7	Nitric Oxide Synthase (NO Synthase)IBA 01/2017 - 05/2002
6	Blood Glucose (Blood Sugar)IBA 01/2018 - 06/2002
5	sapropterin (tetrahydrobiopterin)FDA Link 01/2017 - 03/2010
5	Proteins (Proteins, Gene)FDA Link 01/2017 - 05/2006
5	Reactive Oxygen Species (Oxygen Radicals)IBA 04/2014 - 05/2003
5	Glucose (Dextrose)FDA LinkGeneric 07/2013 - 05/2003
4	sepiapterinIBA 01/2016 - 03/2010
4	arginine methyl esterIBA 01/2010 - 07/2005
4	HeliumIBA 10/2009 - 08/2008
4	AtractylosideIBA 09/2008 - 12/2005
4	WortmanninIBA 09/2007 - 01/2005
3	GTP Cyclohydrolase (GTP Cyclohydrolase I)IBA 01/2017 - 01/2013
3	Mitochondrial Permeability Transition PoreIBA 10/2015 - 05/2006
3	Naloxone (Narcan)FDA LinkGeneric 10/2009 - 03/2003
3	Morphine (MS Contin)FDA LinkGeneric 10/2009 - 03/2003
3	NG-Nitroarginine Methyl Ester (L-NAME)IBA 09/2008 - 05/2002
3	Potassium Channels (Potassium Channel)IBA 08/2008 - 01/2002
3	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 08/2006 - 07/2003
3	1- Methyl- 4- phenyl- 1,2,3,6- tetrahydropyridine (MPTP)IBA 05/2006 - 12/2005
3	Ethanol (Ethyl Alcohol)IBA 04/2004 - 04/2002
2	Streptozocin (Streptozotocin)FDA Link 01/2016 - 08/2004
2	EnzymesIBA 09/2015 - 01/2013
2	Acetylcysteine (Siran)FDA LinkGeneric 04/2014 - 06/2003
2	L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA 01/2013 - 11/2011
2	Heat-Shock Proteins (Heat-Shock Protein)IBA 11/2011 - 03/2010
2	Opioid Receptors (Opioid Receptor)IBA 10/2009 - 10/2005
2	Oxygen (Dioxygen)IBA 08/2009 - 05/2002
2	Phosphotransferases (Kinase)IBA 09/2007 - 02/2006
2	2- (2- amino- 3- methoxyphenyl)- 4H- 1- benzopyran- 4- oneIBA 09/2007 - 08/2006
2	KATP ChannelsIBA 09/2006 - 08/2004
2	Pharmaceutical PreparationsIBA 08/2006 - 03/2003
2	Dimethyl Sulfoxide (DMSO)FDA LinkGeneric 08/2006 - 01/2005
2	Cyclosporine (Ciclosporin)FDA LinkGeneric 05/2006 - 12/2005
2	barbituric acid (barbiturate)IBA 02/2006 - 03/2004
2	Cytochromes c (Cytochrome c)IBA 11/2005 - 10/2005
2	salicylhydroxamic acid (SHAM)IBA 10/2005 - 05/2004
2	PotassiumIBA 08/2004 - 09/2002
2	Celecoxib (Celebrex)FDA Link 03/2004 - 03/2004
2	Superoxides (Superoxide)IBA 04/2003 - 12/2002
2	Opioid Analgesics (Opioids)IBA 03/2003 - 09/2002
1	Halothane (Fluothane)FDA Link 01/2018
1	NAD (NADH)IBA 01/2018
1	p38 Mitogen-Activated Protein KinasesIBA 01/2017
1	Nitric Oxide Synthase Type I (Neuronal Nitric Oxide Synthase)IBA 01/2017
1	CitrullineIBA 01/2016
1	ArginaseIBA 01/2016
1	serum P-component (CIt)IBA 01/2016
1	Citric Acid (Citrate)FDA LinkGeneric 01/2016
1	BuffersIBA 01/2016
1	RNA-Directed DNA Polymerase (Reverse Transcriptase)IBA 09/2015
1	2,4-diaminohypoxanthineIBA 09/2015
1	Guanosine Triphosphate (GTP)IBA 09/2015
1	OzoneIBA 09/2015
1	Mitochondrial DNA (mtDNA)IBA 04/2014
1	AntioxidantsIBA 04/2014
1	Hemeproteins (Heme Protein)IBA 09/2013
1	Apolipoprotein A-I (Apolipoprotein A1)IBA 07/2013
1	Octoxynol (Triton X 100)IBA 01/2013
1	7,8-dihydrobiopterinIBA 01/2013
1	N 30IBA 12/2010
1	Ketamine FDA LinkGeneric 10/2009
1	Methanol (Carbinol)IBA 08/2009
1	NitritesIBA 08/2009
1	monorden (radicicol)IBA 02/2009
1	geldanamycinIBA 02/2009

Therapy/Procedure

9	Microspheres (Microsphere) 12/2007 - 01/2002
9	Stents 06/2006 - 12/2002
4	Cardiopulmonary Bypass (Heart-Lung Bypass) 12/2010 - 10/2009
3	Critical Care (Surgical Intensive Care) 08/2010 - 10/2009
2	Ischemic Postconditioning 05/2006 - 01/2005